Dextran (10K), Flamma® 675

Catalog No. RSC0312
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5 mg $200.00
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Description

Dextran (10K) Flamma® 675 is a fluorescent dextran that 10000 dalton dextran is conjugated with Flamma® 675. Fluorescent dextran conjugates are being utilized in a variety of biological studies such as cell lineage tracing in live cells, intercellular communication examination, vascular permeability, tracking endocytosis, and blood–brain barrier integrity. Dextran (10K) can be transported over long distance and can be applied to cut and fix nerves and brain tissues. Dextran (10K), Flamma® 675 might be utilized in a range of biochemical and biomedical applications, including for analyzing fluid-phase endocytosis, for tracing cell lineage, for examining intercellular communications, and for investigating vascular permeability and blood–brain barrier integrity. 

Specifications

Fluorophore: Flamma® 675

Application: Neural tracing, cell lineage tracing, tracking endocytosis

Excitation/Emission Max.(nm): 675/691 nm

Storage conditions: 4℃, protect from light

Citation & Reference

1. DWIGHT M. NANCE. Fluorescent Dextrans as Sensitive Anterograde Neuroanatomical Tracers: Applications and Pitfalls. Brain Res Bull 25.1 (1990): 139-45.


2. Anne-Marie Ellegaard. Visualizing Lysosomal Membrane Permeabilization by Fluorescent Dextran Release. Cold Spring Harb Protoc 2015.10 (2015): 900-3.


3. M.J. Dolleman-Van der Weel. Multiple anterograde tracing, combining Phaseolus vulgaris leucoagglutinin with rhodamine- and biotin-conjugated dextran amine. J Neurosci Methods 51.1 (1994): 9-21.

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