ICG Thiol

Catalog No. PWT1301
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1 mg $200.00
5 mg $650.00
25 mg $2,400.00
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Description

ICG Thiol is an inactive form of near infrared (NIR) fluorescent dye and used to generate a stable fluorescence signal in bioimaging. The thiol is attached to ICG fluorophore trough a spacer. NIR fluorescence allows to observe the deep image from the surface of skin and being utilized in a wide range of research fields. The maxima of Ex/Em values are at 785/812 nm. ICG might be excited using 750-800 nm laser line or LED and displays excellent optical property. ICG thiol can be labeled to biomolecules through a disulfide bond formation with thiol of cysteine residue or can be utilized as a reference standard for dye-conjugates. 

Specifications

Fluorophore: ICG

Functional group: Thiol

Excitation/Emission Max.(nm): 785/812

Extinction coefficient: ≥ 163,000 cm-1M-1

CF280: 0.05

Appearance: Green Solid

Molecular Weight: 790.09 g/mol

Solubility: DMF, DMSO

Storage conditions: -20 ℃, protect from light



Citation & Reference

1. Masashi Gotoh. Development of a canine model of pulmonary emphysema and imaging of the emphysematous lung with infrared thoracoscopy. J Thorac Cardiovasc Surg 126.6 (2003): 1916-21.


2. Aaron M. Mohs. An integrated widefield imaging and spectroscopy system for contrast-enhanced, image-guided resection of tumors. IEEE Trans Biomed Eng 62.5 (2015): 1416-24.


3. Mohammed Hassan. Near Infrared Fluorescence Imaging with ICG in TECAB Surgery Using the da Vinci Si Surgical System in a Canine Model. J Card Surg 27.2 (2012): 158-162.


4. R. C. Benson. Fluorescence properties of indocyanine green as related to angiography. Phys Med Biol 23.1 (1978): 159-63.


5. Mitsuharu Miwa. The Principle of ICG Fluorescence Method. The Open Surgical Oncology Journal 2 (2010): 26-28.

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