BBBFlamma® AD is a far-red fluorescent dye targeting for amyloid beta (AB) plaque, developed by BioActs’ cutting-edge technology. Together with tau protein, AB is an important biomarker of Alzheimer, thus real-time fluorescence monitoring of AB in brain and cerebrospinal fluid (SCF) might be advantageous in the study of this devastating disease. BBBFlamma® AD effectively penetrates blood-brain barrier and selectively bind to AB plaque thereby providing real-time fluorescent AB imaging. The maxima of Ex/Em values are at 546/656 nm. BioActs offers BBBFlamma® AD as an efficient fluorescent AB plaque imaging agent for both in vitro and in vivo studies. 


Fluorophore: BBBFlamma® AD

Excitation/Emission Max.(nm): 570/650

Appearance: Purple Solid

Molecular Weight: 529.24 g/mol

Solubility: DMSO, DMF

Storage conditions: -20 ℃, protect from light

Citation & Reference

  1.  Synthesis and evaluation of curcumin-based near-infrared fluorescent probes for the in vivo optical imaging of amyloid-β plaques., Yong Dae Park, Mayank Kinger, Changho Min, Sang Yeob Lee, Youngjoo Byun, Jin Woo Park, Jongho Jeon, Bioorganic Chemistry.,  2021, 115, 105 167


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