Description

Flamma® Fluors 800 Vinylsulfone is pH insensitive reactive form of near infrared (NIR) fluorescent dye and used to generate a stable fluorescence signal with high signal-to-noise ratio. The maxima of Ex/Em values are at 774/789 nm, similar to that of IRDye 800, Cy7.5 and CF770. Flamma 800 dyes might be excited using 750 or 785 nm laser line or dye-pumped laser excitation and the emission occurs at NIR region. Flamma Fluors 800 is ideal for protein, antibody and nucleic acid labeling for in vitro imaging and other fluorescence detection methods. Vinylsulfones readily react with primary amines of amino-modified oligonucleotides or of proteins to form a stable amino linkage between dye and the biomolecule. We offer Flamma Fluors 800 Vinylsulfone for labeling of antibodies, peptides, proteins, ligands and in vivo NIR imaging.  

Specifications

Fluorophore: Flamma® Fluors 800

Reactive group: Vinylsulfone

Excitation/Emission Max.(nm): 774/789 

Spectrally similar dyes: Cy7.5, DyLight800, IRDye800

Extinction coefficient: ≥ 191,000 cm-1M-1

CF280: 0.03

Appearance: Green Solid

Molecular Weight: 1117.25 g/mol

Solubility: Water, DMF, DMSO

Storage conditions: 4 ℃, protect from light

Citation & Reference

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19. Yhee, Ji Young. Cancer-targeted MDR-1 siRNA delivery using self-cross-linked glycol chitosan nanoparticles to overcome drug resistance. Journal of Controlled Release 198 (2015): 1-9.


20. Park, Jin Woo. Wide-Ranged Fluorescent Molecular Weight Size Markers for Electrophoresis. Bulletin of the Korean Chemical Society 34.1 (2013): 29-30.


21. Huang, Xinglu. Multiplex Imaging of an Intracellular Proteolytic Cascade by using a Broad?Spectrum Nanoquencher. Angewandte Chemie International Edition 51.7 (2012): 1625-1630. 

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