qFlamma® Black01 Dichlorotriazine

Catalog No. QWR1001
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1 mg $523.00
5 mg $1,822.00
25 mg $6,783.00
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Description

qFlamma® Black01 Dichlorotriazine is a hydroxyl group reactive form of universal dark quencher that the range of absorption covers from 400 to 800 nm with no native fluorescence. Black01 quencher displays high absorption coefficient, superb stability and aqueous solubility. Dichlorotriazines are among the few reactive groups that are reported to react directly with polysaccharides and other alcohols in aqueous solution, provided that the pH is >9 and other nucleophiles are not present. We offer qFlamma® Black01 dichlorotriazine for the labeling of polysaccharides and alcohols in designing probes consisting of spectrally paired fluorophore and quencher for multiplexed bio-analysis. 

Specifications

Functionality: Dark quencher

Reactive group: Dichlorotriazine

Absorption max. (nm): 484

Absorption range (nm): 400 ~ 800

Appearance: Green Solid

Molecular Weight: 911.79 g/mol

Solubility: Water, DMF, DMSO

Storage conditions: -20 ℃, protect from light



Citation & Reference

1. Arnaud Chevalier. Bioconjugatable Azo-Based Dark-Quencher Dyes: Synthesis and Application to Protease-Activatable Far-Red Fluorescent Probes. Chemistry 19.5 (2013): 1686-99.

 

2. Arnaud Chevalier. Universal Dark Quencher Based on “Clicked” Spectrally Distinct Azo Dyes. Org. Lett 2013 15.23 (2013): 6082–6085.


3. Arnaud Chevalier. Straightforward synthesis of bioconjugatable azo dyes. Part 1: Black Hole Quencher-1 (BHQ-1) scaffold. Tetrahedron Letters 55.50 (2014): 6759-6763.

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