qFlamma® Black01 Vinylsulfone

Catalog No. QWA1001
PACKING UNIT

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1 mg $88.00
5 mg $205.00
25 mg $441.00
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Description

qFlamma® Black01 Vinylsulfone is an amine  reactive form of universal dark quencher that the range of absorption covers from 400 to 800 nm with no native fluorescence. Black01 quencher displays high absorption coefficient, superb stability and aqueous solubility. Vinylsulfone reactive group, developed by BioActs’ leading technology, is stable in a wide range of pH and at the high temperature and reacts with primary amines of probes, proteins, peptides or amino-modified nucleotides to form a stable amino linkage between quencher and the biomolecule.We offer qFlamma® Black01 vinylsulfone as a universal dark quencher in the construction of a variety of hybridization and custom-synthesized activatable probes for multiplexed bio-analysis, PCR, nucleic acid hybridization, etc. 

Specifications

Functionality: Dark quencher

Reactive group: Vinylsulfone

Absorption max. (nm): 484

Absorption range (nm): 400 ~ 800

Appearance: Green Solid

Molecular Weight: 838.92 g/mol

Solubility: Water, DMF, DMSO

Storage conditions: -20 ℃, protect from light



Citation & Reference

1. Lim, Chang-Keun. Phthalocyanine-aggregated polymeric nanoparticles as tumor-homing near-infrared absorbers for photothermal therapy of cancer. Theranostics 2.9 (2012): 871-879.


2. Park, Jin Woo. Novel cyanine dyes with vinylsulfone group for labeling biomolecules. Bioconjugate chemistry 23.3 (2012): 350-362.


3. Lim, Chang-Keun. Gadolinium-coordinated elastic nanogels for in vivo tumor targeting and imaging. Biomaterials 34.28 (2013): 6846-6852.


4. Keunsoo Jeong. Poly (oxyethylene sugaramide) s: unprecedented multihydroxyl building blocks for tumor-homing nanoassembly. Journal of Materials Chemistry B 1.28 (2013): 3437-3442.


5. Lee, So Jin. TNF-? gene silencing using polymerized siRNA/thiolated glycol chitosan nanoparticles for rheumatoid arthritis. Molecular Therapy 22.2 (2014): 397-408.


6. Yoon, Hong Yeol. Photo-crosslinked hyaluronic acid nanoparticles with improved stability for in vivo tumor-targeted drug delivery. Biomaterials 34.21 (2013): 5273-5280.


7. Park, Solji. Amphiphilized poly (ethyleneimine) nanoparticles: a versatile multi-cargo carrier with enhanced tumor-homing efficiency and biocompatibility. Journal of Materials Chemistry B 3.2 (2015): 198-206.


8. Lee, Eunjung. Co-delivery of chemosensitizing siRNA and an anticancer agent via multiple monocomplexation-induced hydrophobic association. Journal of Controlled Release 210 (2015): 105-114. 

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