ICG Vinylsulfone

Catalog No. POA1616
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1 mg $138.00
5 mg $420.00
25 mg $1,575.00
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Description

ICG Vinylsulfone is pH insensitive amine-reactive near infrared (NIR) fluorescent dye and used to generate a stable fluorescence signal in bioimaging. NIR fluorescence allows to observe the deep image from the surface of skin and being utilized in a wide range of research fields. Vinylsulfone reactive group, developed by BioActs’ leading technology, is stable in a wide range of pH and at the high temperature. The maxima of Ex/Em values are at 785/812 nm. ICG might be excited using 750-800 nm laser line or LED and displays excellent optical property. Vinylsulfones readily react with primary amines of amino-modified oligonucleotides or of proteins to form a stable amino linkage between dye and the biomolecule. BioActs provides ICG dye for various biological research and medical diagnostics. We offer ICG Vinylsulfone for labeling of antibodies, peptides, proteins, ligands, and amplification substrates optimized for cellular labeling and NIR imaging. 

Specifications

Fluorophore: ICG

Reactive group: Vinylsulfone

Excitation/Emission Max.(nm): 785/812

Extinction coefficient: 240,000 cm-1M-1

CF280: 0.05

Appearance: Green Solid

Molecular Weight: 848.3 g/mol

Solubility: DMF, DMSO

Storage conditions: 4 ℃, protect from light



Citation & Reference

1. Masashi Gotoh. Development of a canine model of pulmonary emphysema and imaging of the emphysematous lung with infrared thoracoscopy. J Thorac Cardiovasc Surg 126.6 (2003): 1916-21.


2. Aaron M. Mohs. An integrated widefield imaging and spectroscopy system for contrast-enhanced, image-guided resection of tumors. IEEE Trans Biomed Eng 62.5 (2015): 1416-24.


3. Mohammed Hassan. Near Infrared Fluorescence Imaging with ICG in TECAB Surgery Using the da Vinci Si Surgical System in a Canine Model. J Card Surg 27.2 (2012): 158-162.


4. R. C. Benson. Fluorescence properties of indocyanine green as related to angiography. Phys Med Biol 23.1 (1978): 159-63.


5. Mitsuharu Miwa. The Principle of ICG Fluorescence Method. The Open Surgical Oncology Journal 2 (2010): 26-28.

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