ICG NHS ester

Catalog No. POS1604
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1 mg $121.00
5 mg $347.00
25 mg $735.00
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Description

ICG NHS ester is an amine-reactive form of near infrared (NIR) fluorescent dye and used to generate a stable fluorescence signal in bioimaging. NIR fluorescence allows to observe the deep image from the surface of skin and being utilized in a wide range of research fields. The maxima of Ex/Em values are at 785/811 nm. ICG might be excited using 750-800 nm laser line or LED and displays excellent optical property. NHS esters readily react with amine-modified oligonucleotides or amino groups of proteins, i.e. the ε-amino groups of lysine or the amine terminus of nucleotides to form a chemically stable amide bond between dye and the biomolecule. We offer ICG NHS ester for labeling of antibodies, peptides, proteins, ligands, and amplification substrates optimized for cellular labeling and NIR imaging. 

Specifications

Fluorophore: ICG

Reactive group: NHS ester

Excitation/Emission Max.(nm): 785/811

Extinction coefficient: ≥ 218,000 cm-1M-1

CF280: 0.05

Appearance: Green Solid

Molecular Weight: 828.03 g/mol

Solubility: DMF, DMSO

Storage conditions: -20 ℃, protect from light



Citation & Reference

1. Masashi Gotoh. Development of a canine model of pulmonary emphysema and imaging of the emphysematous lung with infrared thoracoscopy. J Thorac Cardiovasc Surg 126.6 (2003): 1916-21.


2. Aaron M. Mohs. An integrated widefield imaging and spectroscopy system for contrast-enhanced, image-guided resection of tumors. IEEE Trans Biomed Eng 62.5 (2015): 1416-24.


3. Mohammed Hassan. Near Infrared Fluorescence Imaging with ICG in TECAB Surgery Using the da Vinci Si Surgical System in a Canine Model. J Card Surg 27.2 (2012): 158-162.


4. R. C. Benson. Fluorescence properties of indocyanine green as related to angiography. Phys Med Biol 23.1 (1978): 159-63.


5. Mitsuharu Miwa. The Principle of ICG Fluorescence Method. The Open Surgical Oncology Journal 2 (2010): 26-28.

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